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Recent Development on Computer Aided Tissue Engineering

Recent Development on Computer Aided Tissue Engineering

Wei Sun, Pallavi Lal

Computer-aided tissue engineering (CATE) is a field that uses computer technology, such as imaging and computer-aided design (CAD), to create and manufacture biological scaffolds. These technologies help with surgical planning, anatomical modeling, and the 3D reconstruction of tissues for repair and replacement.

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A Three-Dimensional, Anatomically Detailed Foot Model

A Three-Dimensional, Anatomically Detailed Foot Model

A detailed 3-D reconstruction of a human foot was created from CT images, including individual bone meshes, soft tissue, and cartilage. Principal axes and relative angles of bones were calculated to quantify foot shape and provide an anatomical basis for future finite element modeling.

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Finite Element Modeling of the Human Thoracolumbar Spine

Finite Element Modeling of the Human Thoracolumbar Spine

This study developed a new finite element modeling technique to accurately predict the biomechanical properties of human vertebrae. By calibrating the model's shell properties to experimental data, the researchers created a reliable tool for studying vertebral behavior and improving clinical fracture risk assessments.

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Three-Dimensional Finite Element Modeling of Dilated Human Ascending Aorta

Three-Dimensional Finite Element Modeling of Dilated Human Ascending Aorta

Ajay Bohra, Thoralf M. Sundt, and Ruth J. Okamoto

This study uses a patient-specific finite element model of a dilated ascending aorta to investigate the distribution of wall stresses. The research reveals that the complex 3D geometry of the aorta, not just its diameter, is a significant factor in determining the risk of rupture.

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Bone Regeneration and Fracture Healing: Experience With Distraction Osteogenesis Model

Bone Regeneration and Fracture Healing: Experience With Distraction Osteogenesis Model

This study uses distraction osteogenesis in a rabbit model to investigate how mechanical forces influence bone formation. The results show that bone regeneration is highly sensitive to changes in the strain environment, suggesting that physical forces play a crucial role in the healing process.

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