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Tools for Deformable Image Registration

Tools for Deformable Image Registration

Anton Edis Bowden

This dissertation develops computational tools to improve “Warping,” a continuum mechanics-based image registration technique for biomechanical analysis. The tools enhance accuracy in calculating tissue stress and strain (e.g., spinal disc, fingerpad) and introduce methods to quantitatively assess registration quality and reliability.

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Virtual Prototyping and Testing for Medical Device Development

Virtual Prototyping and Testing for Medical Device Development

Robert G. Whirley and Michael V. Chobotov

This patent outlines a system for virtually designing and testing medical devices like stents using computer simulations. The process involves creating a finite element model based on a device's design and a patient's CT or MRI scan, and then applying nonlinear analysis to predict how the device will perform under physiological loads. This biomechanical simulation allows for the early identification of design flaws, accelerating the development of safer and more effective medical implants.

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The Effect of Design Variations on Stresses in Total Ankle Arthroplasty

The Effect of Design Variations on Stresses in Total Ankle Arthroplasty

Karol Galik

This is a biomechanical dissertation that utilizes the finite element method (FEM) to analyze how design variations in total ankle arthroplasty (TAA) implants affect stresses and strains in both the implant components and the surrounding bones. The research compares two designs of the Agility ankle implant to understand their biomechanical performance and potential for causing bone failure or implant subsidence.

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Probabilistic Response of a Validated and Verified Parametric Cervical Spine Finite Element Model

Probabilistic Response of a Validated and Verified Parametric Cervical Spine Finite Element Model

This paper details the development of a probabilistic finite element model of the cervical spine, designed to account for biological variability and uncertainty in geometry and material properties. The model was used to predict a range of potential responses under flexion and extension, with the goal of providing a more realistic assessment of injury probability in biomechanics research.

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Mechanobiology of Mandibular Distraction Osteogenesis: Finite Element Analyses with a Rat Model

Mechanobiology of Mandibular Distraction Osteogenesis: Finite Element Analyses with a Rat Model

This page introduces a biomechanics study that uses finite element analysis and a rat model to characterize the local mechanical environment during mandibular distraction osteogenesis.

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