Publications

Publications

Quantification of 3D Left Ventricular Deformation using Hyperelastic Warping

A.I. Veress, J.A. Weiss, G.J. Klein, G.T. Gullberg

This paper validates Hyperelastic Warping, a computational technique that measures left-ventricle strain from MRI and PET by deforming a finite element heart model. It accurately calculates myocardial stretching without invasive markers, providing a non-invasive tool to assess ventricular mechanics and improve understanding of cardiac function.

Effects of Bone Cement Volume and Distribution on Vertebral Stiffness After Vertebroplasty

This paper uses sophisticated finite element analysis to study the biomechanics of vertebroplasty, a procedure for repairing spinal fractures with bone cement. The computer simulations show that only a small amount of cement (~15% of the vertebra's volume) is needed to restore the bone's original stiffness. Using more cement can make the vertebra much stiffer than its original state and, if placed asymmetrically, can lead to unstable "toggling" motions under load.

A Computer Model of Normal Conduction in the Human Atria

David M. Harrild, Craig S. Henriquez

This research details the creation of an advanced computer model of the human atria that simulates the biomechanics of its electrical activation. By incorporating realistic anatomy and the anisotropic electrical conductivity of different muscle bundles, the model accurately reproduces the complex patterns of normal heart rhythm. This powerful simulation tool helps explain how the physical structure of the atria governs its electrical function and provides a new platform for studying arrhythmias.

Finite Element Modeling Used to Study Stress Distribution on the Foot

This paper develops a patient-specific finite element model of the forefoot from MRI scans to study stress distribution during walking. It compares internal stresses in diabetic vs. non-diabetic feet, offering insight into how anatomical and material changes influence injury risk.

Design and Application of a Test System for Viscoelastic Characterization of Collagen Gels

This research presents a new testing device designed to measure the viscoelastic properties of collagen gels, which are widely used in tissue engineering. Using a combination of physical experiments and finite element analysis, the study quantifies how the stiffness and energy dissipation of the gels change with different collagen concentrations and loading speeds. This work provides a crucial biomechanical framework for understanding and controlling the properties of engineered tissues.