Biomechanical

Publications

Three-dimensional Finite Element Modeling of Ligaments: Technical Aspects

This paper serves as a detailed technical guide to the process of creating and validating three-dimensional finite element models of human ligaments. It covers the entire biomechanical modeling pipeline, from obtaining geometry via medical imaging to applying advanced constitutive models that capture the tissue's complex properties. A key focus is a novel method for incorporating the ligament's natural pre-tension (in situ strain) into the models which is critical for achieving accurate results.

Effect of High +gz Accelerations on the Left Ventricle

K. Behdinan, B. Tabarrok, W.D. Fraser

This study uses a detailed FE< to simulate the biomechanical effects of high G-forces, like those experienced by fighter pilots, on the human heart's left ventricle. The analysis reveals that these accelerations cause the ventricle to stretch significantly and produce high, non-uniform stress patterns, particularly at the top of the heart near its attachments. This computational approach helps to understand the potential for mechanical tissue damage under extreme aerospace conditions.

Tools for Deformable Image Registration

Anton Edis Bowden

This dissertation develops computational tools to improve “Warping,” a continuum mechanics-based image registration technique for biomechanical analysis. The tools enhance accuracy in calculating tissue stress and strain (e.g., spinal disc, fingerpad) and introduce methods to quantitatively assess registration quality and reliability.

Virtual Prototyping and Testing for Medical Device Development

Robert G. Whirley and Michael V. Chobotov

This patent outlines a system for virtually designing and testing medical devices like stents using computer simulations. The process involves creating a finite element model based on a device's design and a patient's CT or MRI scan, and then applying nonlinear analysis to predict how the device will perform under physiological loads. This biomechanical simulation allows for the early identification of design flaws, accelerating the development of safer and more effective medical implants.

The Effect of Design Variations on Stresses in Total Ankle Arthroplasty

Karol Galik

This is a biomechanical dissertation that utilizes the finite element method (FEM) to analyze how design variations in total ankle arthroplasty (TAA) implants affect stresses and strains in both the implant components and the surrounding bones. The research compares two designs of the Agility ankle implant to understand their biomechanical performance and potential for causing bone failure or implant subsidence.