Biomechanical

Publications

Modeling the biomechanical and injury response of human liver parenchyma under tensile loading

This biomechanical study utilized uniaxial tensile tests and specimen-specific finite element models to characterize the material and failure properties of human liver parenchyma under various loading rates. The research developed an approach that accurately models both the biomechanical response and the tearing behavior of liver tissue, significantly improving the assessment of abdominal injury risk in crash events.

Material Properties Of The Infant Skull And Application

This biomechanical study characterizes the age-dependent material properties of infant skull and suture tissue through mechanical testing and integrates this data into three-dimensional finite element models of the pediatric head. These models simulate impact scenarios to investigate the sensitivity of skull and brain strains to impact direction, thereby advancing the understanding of pediatric head injury biomechanics and fracture risk.

Musculotendon variability influences tissue strains

Niccolo M. Fiorentinoa and Silvia S. Blemker

"Musculotendon variability influences tissue strains experienced by the biceps femoris long head muscle during high-speed running"

THE EFFECTS OF APONEUROSIS GEOMETRY ON STRAIN INJURY SUSCEPTIBILITY EXPLORED WITH A 3D MUSCLE MODEL

Michael Rehorn, Silvia Blemker

This biomechanical study investigates how the geometry of aponeuroses affects strain distributions and injury susceptibility in the biceps femoris longhead muscle. Through 3D finite element modeling, it was found that narrower proximal aponeuroses lead to increased fiber strain near injury-prone regions. The work provides new insights into the architectural basis for common hamstring injuries.

Multiscale models of skeletal muscle

"Multiscale models of skeletal muscle reveal the complex effects of muscular dystrophy on tissue mechanics and damage susceptibility" This study uses a multiscale biomechanical model to reveal how DMD-driven microstructural changes affect muscle tissue mechanics and damage vulnerability. By linking fiber-level alterations to tissue strain patterns, it highlights key biomechanical mechanisms underlying disease progression and muscle fragility.