Abstract:
This comprehensive volume presents advanced computational strategies for patient-specific modeling of the cardiovascular system, emphasizing biomechanics and personalized medicine approaches. Utilizing state-of-the-art imaging and numerical methods, the contributions explore modeling techniques from the sub-cellular to the whole-organ level to diagnose, treat, and manage cardiovascular diseases more effectively. Several chapters provide detailed analyses on biomechanical phenomena such as myocardial deformation, mechanical stress distribution in heart tissues, and wall stress in aneurysms, employing finite element methods to simulate realistic physiological scenarios. For instance, studies presented include biomechanical modeling of heart failure conditions, detailed exploration of stress and strain distributions in normal and failing hearts, and computational strategies to evaluate abdominal aortic aneurysm rupture risk. The book highlights the clinical utility of patient-specific biomechanical modeling, illustrating how such approaches can refine treatments, enhance clinical decision-making, and improve patient outcomes in cardiovascular care through precise, personalized simulations.
